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Dr. Lisa S. Webb
Research Interests
Dr. Webb is working with Dr. Harold J. Grau (a CNU colleague) to conduct a molecular genetic analysis of geographically isolated populations of cotton stainer insects (Dysdercus andreae). The hypothesis driving this research is that geographically isolated populations of insects will be genetically diverse. We, and our undergraduate students, are using forensic and biotechnological methods to identify and document these genetic polymorphisms.
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Students perform an agarose gel electrophoresis |
DNA fluorescing on an ethidium bromide stained agarose gel |
Students perform an agarose gel electrophoresis |
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Through a collaborative effort with Dr. Dabney K. Johnson (at the Oak Ridge National Laboratory), I am continuing a project to analyze two strains of mice that have mutations in the prmt3 (protein arginine methyltransferase) gene on Mouse Chromosome 7. These mice have a severe neurological phenotype, with homozygotes exhibiting profound seizures and lethality by 15 to 18 days. This project will involve sequencing the genomic region surrounding the prmt3 locus and a biochemical and histological analysis of the mutants. The mouse work will be performed at the “Mouse House” at ORNL during the summers, and the molecular and histological work will be performed at CNU with undergraduates during the academic year. |
Summer 2006
research project is funded by the
Department of Energy’s FaST Program > |
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